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Weight Loss Forum / Low Carb / January 2009

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LC and DNA

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RRzVRR - 17 Jan 2009 13:31 GMT
Spotted this brief story/headline this morning... will have to look into
it further.
=================================

Genes remember sugar hit: Australian research
Fri Jan 16, 1:20 pm ET

SYDNEY (AFP) – Human genes remember a sugar hit for two weeks, with
prolonged poor eating habits capable of permanently altering DNA,
Australian research has found.

A team studying the impact of diet on human heart tissue and mice found
that cells showed the effects of a one-off sugar hit for a fortnight, by
switching off genetic controls designed to protect the body against
diabetes and heart disease.

"We now know that chocolate bar you had this morning can have very acute
effects, and those effects can continue for up to two weeks," said lead
researcher Sam El-Osta, from the Baker IDI Heart and Diabetes Institute.

"These changes continue beyond the meal itself and have the ability to
alter natural metabolic responses to diet," he told Australian
Associated Press Friday.

Regular poor eating would amplify the effect, said El-Osta, with genetic
damage lasting months or years, and potentially passing through bloodlines.

The study's findings were reported in the Journal of Experimental Medicine.
Doug Freyburger - 18 Jan 2009 22:18 GMT
RRzVRR <rrZ...@ix.netcom.com> quoted:

> Spotted this brief story/headline this morning... will have to look into
> it further.
[quoted text clipped - 4 lines]
>
> SYDNEY (AFP) – Human genes remember a sugar hit for two weeks,

Huh.  Two weeks again.  Funny how studies like this just happen
to en up matching the two weeks of Atkins Induction and the
starting phase of so many other plans.  The list of explanations
for the initial phase is two weeks continues to grow long after
the plans are written.

> with
> prolonged poor eating habits capable of permanently altering DNA,

I think this is called "epigenetics".  It has something to do with
ways that genes get expressed because of non-DNA stuff bound
to the genes.  It can effect a couple of generations but is not
permanent across many generations.  IF this is about
epigenetics ...

> "These changes continue beyond the meal itself and have the ability to
> alter natural metabolic responses to diet," he told Australian
> Associated Press Friday.

We low carbers are other than shocked by this news.

> Regular poor eating would amplify the effect, said El-Osta, with genetic
> damage lasting months or years, and potentially passing through bloodlines.

Sounds like medical histories that involve reversing insulin
resistance, doesn't it?
 
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