>> > Google for "leptin reset" discussions. Staying too low in carb intake
>> > too long tends to reduce the levels of thyroid T3 and/or leptin.
[quoted text clipped - 5 lines]
>
> Any chance of a translation for the great unwashed?
> It depends on what translation you mean. There are two time scales to
> be found.
[quoted text clipped - 3 lines]
> in. It's one of many reasons why Atkins Induction lasts that long by
> default.
You seem to be confusing the fact that some studies don't check for T3
for two weeks with that being how long it takes to fall. This abstract
compares with all the others I've seen that measure T3 upon initiation
of fasting. Other studies of ketosis onset in type 1 diabetics measure
mere hours for T3 to drop measurably.
Endokrinologie. 1981 Mar;77(1):70-8.
Effects of total fasting in obese women. IV. Response of serum
triiodothyronine (T3) and reverse triiodothyronine (rT3) to administered T3.
Límanová Z, Sonka J, Kratochvíl O, Wilczek H, Marek J.
Abstract
Serum levels of T4, T3, rT3, RT3U and TSH were estimated in 12 obese
women in the course of a 14-day fasting. Seven of these patients were
treated with T3 in a daily dose of 60--80 micrograms. Fasting led to a
small increase of serum T4, while fasting combined with T3
administration was accompanied by a small decrease of serum T4.
*************Serum T3 decreased in the course of the first 2 days of
fasting to 40--50% of initial values and remained at this low level up
to the 15th day of fasting.*****************
In the T3 treated group a prompt increase of serum T3 was recorded
(+80%), followed by a steady decrease, reaching the control values on
day 15, in spite of a continuous T3 administration. Serum rT3 in the
untreated fasting group steadily increased up to the 12th day (+43%) and
then dropped below the control value (-28%). In the treated group after
a non-significant increase (+22%), a decrease of serum rT3 was also
observed (-42%). Fasting was accompanied by a tendency to increased
serum RT3U values, in the T3 treated group no change occurred. TSH in
the untreated fasting women remained practically unchanged while T3
administration was accompanied by a tendency to a transient decrease.
The heart rate showed a non-significant tendency to increase in the T3
treated group and the last week of fasting was also accompanied in
several patients by a larger weight loss. These results suggest that in
addition to an enhanced synthesis of rT3 to the detriment of a decreased
production of T3 from T4, an increased catabolism of administered T3 and
of endogenous rT3 is involved in a strict calorie restriction. An
abortive T3-TRH-TSH feed-back may also operate in these conditions.
PMID: 7227325 [PubMed - indexed for MEDLINE]