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Weight Loss Forum / Low Carb / March 2004Splenda tablets - Why can't Johnson & Johnson sell them in the US?
As you may know, Splenda is available in a tablet form in many countries. http://www.jnjaust.com.au/brands/splenda_prod.jsp?rid=cat220231&cid=cat20028 Of course these are not available in the US unless you order them from another country with a large shipping charge. http://www.splenda.com/index.jhtml If enough people contacted Johnson & Johnson, maybe they would start selling them here. http://www.splenda.com/vcrc/customer.jhtml;jsessionid=IAUQKNLFEJNXUCQPCCGSUZYKB2 IIQNSC This would be a great product for those of us who travel or just would rather use Splenda than Equal when we eat out. Tell Johnson & Johnson if you would like this product to be available in the US at the regular price. > As you may know, Splenda is available in a tablet form in many > countries. <snip> I didn't know, but I would also have no use for them. If I do use Splenda, it is in cooking. Couldn't use tablets there!  SignatureType 2 http://users.bestweb.net/~jbove/ > > As you may know, Splenda is available in a tablet form in many > > countries. [quoted text clipped - 3 lines] > I didn't know, but I would also have no use for them. If I do use Splenda, > it is in cooking. Couldn't use tablets there! Of course you can. just crush them. Sid... > > > As you may know, Splenda is available in a tablet form in many > > > countries. [quoted text clipped - 6 lines] > > Of course you can. just crush them. Why bother? Too much trouble to do that. SignatureType 2 http://users.bestweb.net/~jbove/ > > > I didn't know, but I would also have no use for them. If I do use > > Splenda, > > > it is in cooking. Couldn't use tablets there! > > Of course you can. just crush them. > > Why bother? Too much trouble to do that. > Type 2 Think of it this way: you're using calories and getting exercise while you're crushing the tablets. Pat in TX > > > > As you may know, Splenda is available in a tablet form in many > > > > countries. [quoted text clipped - 8 lines] > > Why bother? Too much trouble to do that. Because you avoid all the fillers that the other forms have. Sid... > Because you avoid all the fillers that the other forms have. And then I have no bulk! Kinda defeats the purpose. SignatureType 2 http://users.bestweb.net/~jbove/ > > Because you avoid all the fillers that the other forms have. > > > And then I have no bulk! Kinda defeats the purpose. Actually it doesn't. the bulk fillers maltodextrin and dextrose are so fine that once dissolved in water provide no bulk or texture to the end product unlike sugar. The fillers are there to allow splenda to measure like sugar. Since the tablets = 1 tsp it is simple just to count them. Sid... > Actually it doesn't. the bulk fillers maltodextrin and dextrose are so fine > that once dissolved in water provide no bulk or texture to the end product > unlike sugar. > > The fillers are there to allow splenda to measure like sugar. Since the > tablets = 1 tsp it is simple just to count them. Since the only time I'm using Splenda, I'm using about a cup at a time, that would take me forever! I don't know how many teaspoons are in a cup and I'm not about to count them. I also use Splenda maybe 4-5 times a year at the most. So it using the product I already have is not a problem for me. SignatureType 2 http://users.bestweb.net/~jbove/ >> I didn't know, but I would also have no use for them. If I do use >> Splenda, it is in cooking. Couldn't use tablets there! >Of course you can. just crush them. > >Sid... Yep, I do that all the time. My first choice is using a zero-carb liquid splenda syrup, but if there's reason not to add additional liquid to a recipe, I'll crush the tablets with the back of a spoon. Since they're just 0.07 g carb per tablet, they're a lot better than using the powdered stuff. Em > > > As you may know, Splenda is available in a tablet form in many > > > countries. [quoted text clipped - 6 lines] > > Of course you can. just crush them. Or dissolve it in a spoonful of warm water before stirriing it in: crushing those wienie tablets without *sproinging* them across the kitchen is a bit of an adventure. > > > > As you may know, Splenda is available in a tablet form in many > > > > countries. [quoted text clipped - 14 lines] > those wienie tablets without *sproinging* them across the kitchen is a bit > of an adventure. Or simply buy the powder form. Servant to the humblest person in the universe, Andrew -- Dr. Andrew B. Chung, MD/PhD Board-Certified Cardiologist http://www.heartmdphd.com/ ** Who is the humblest person in the universe? http://makeashorterlink.com/?W1F522557 What is all this about? http://makeashorterlink.com/?J2DB148A7 Is this spam? http://makeashorterlink.com/?N69721867 > > > > > As you may know, Splenda is available in a tablet form in many > > > > > countries. [quoted text clipped - 23 lines] > -- > Dr. Andrew B. Chung, MD/PhD Ah, but that would defeat the purpose! >> > > > > As you may know, Splenda is available in a tablet form in many >> > > > > countries. [quoted text clipped - 27 lines] > > Ah, but that would defeat the purpose! But the powdered form has maltodextrin or maltodextrin and dextrose, and it has a nasty aftertaste. SignatureBob in CT Remove ".x" to reply you are responding to a known quack and usenet kook and troll >> > > > > As you may know, Splenda is available in a tablet form in many >> > > > > countries. [quoted text clipped - 25 lines] > >Ah, but that would defeat the purpose! >As you may know, Splenda is available in a tablet form in many >countries. Forgive my ignorance - but why would you use tablets? I use the packets and the granules all the time. I just can't wait for substitiutes like brown sugar, and maple syrup and other sweet things that can be made w/ splenda. It does seem odd that they would make them in one country, but not another. Are "tablet sweeteners" popular in the UK as packets are here? I personally think the packets of Splenda serve the same purpose, so it would be hard to convince them of the the need to make both available in the US. I think many consumers here equate "tablet" with "medication" and that may be a drawback. > It does seem odd that they would make them in one country, but not > another. Are "tablet sweeteners" popular in the UK as packets are [quoted text clipped - 4 lines] > available in the US. I think many consumers here equate "tablet" with > "medication" and that may be a drawback. I'd rather have the liquid form. SignatureBob in CT Remove ".x" to reply > > It does seem odd that they would make them in one country, but not > > another. Are "tablet sweeteners" popular in the UK as packets are [quoted text clipped - 6 lines] > > I'd rather have the liquid form. I concur. I don't understand the opposition to a calorie free version of this sweetener. > > It does seem odd that they would make them in one country, but not > > another. Are "tablet sweeteners" popular in the UK as packets are [quoted text clipped - 6 lines] > > I'd rather have the liquid form. Equal makes a tablet form and all the stores in this area sell it and have for years. Someone must be buying it. The tablet form of Splenda would be great for people on the go, who eat out often, or who travel extensively and prefer Splenda. Some of us might want the choice and convenience. >>>It does seem odd that they would make them in one country, but not >>>another. Are "tablet sweeteners" popular in the UK as packets are [quoted text clipped - 12 lines] > travel extensively and prefer Splenda. Some of us might want the > choice and convenience. I bought 5 packs of 300 tablets from Australia. This was before I knew I could get the liquid. I keep one in my purse for restaurants its very convenient. I also use tablet at home in coffee. Much better then the packets or granular. Now also have the liquid and thankfully have that on hand for recipes. I wouldnt want to carry this around in my purse though, the tablets are better for that. Linda > It does seem odd that they would make them in one country, but not > another. Are "tablet sweeteners" popular in the UK as packets are [quoted text clipped - 4 lines] > available in the US. I think many consumers here equate "tablet" with > "medication" and that may be a drawback. I don't agree with your tablet idea. When I was a little kid, my grandmother and grandfather used to use tablets of saccharin in their iced tea every day. So, the American public has a long history of using sweeteners in tablet form. Oh--and please don't cross post. Pat in TX > > It does seem odd that they would make them in one country, but not > > another. Are "tablet sweeteners" popular in the UK as packets are [quoted text clipped - 13 lines] > > Pat in TX The tablets are great. less than 1/10 g of carbs ber tablet (1 tsp). Sid... Ryan said this... > It does seem odd that they would make them in one country, but not > another. Are "tablet sweeteners" popular in the UK as packets are > here? You only really find packet sweeteners in restauraunts/cafes. Tablets are the preferred version here in Britain. Splenda comes in 100 and 300 tablet dispensers, neat little things that are ideal for travelling. The granules were available first and both versions have caught on quite successfully. Sales of aspartame based products have fallen significantly. Ratty SignatureLife's Rich Pageant www.flyingrat.net Yes, tablet form sweeteners are popular here. For example, if you see a "sweet n Low" pack in a restaurant, when you open it - two little tablet sweeteners fall out. Personally I use both. At home I have the powdered Splenda. And I carry a tablet dispenser in my handbag. Why? Because not all restaurants carry Splenda, and I have to admit to being a big convert of this brand!!! JD why not try stevia instead? Splenda is a sugar molecule with a chlorine pasted on it. A tasty invention, but is it safe? SignatureWinning against heart attack and stroke http://www.sonoscore.com > why not try stevia instead? Splenda is a sugar molecule with a chlorine > pasted on it. A tasty invention, but is it safe? Stevia is herb, right, but not every herb is safe either... Mirek Stevia has been used for over 1,500 years by young and old people, including pregnant women without any report of harm to my knowledge. This alone make me feel more comfortable using it. Sucralose is new however. Too new for me to feel comfortable with it. http://www.mercola.com/2000/dec/3/sucralose_dangers.htm SignatureWinning against heart attack and stroke http://www.sonoscore.com > Stevia has been used for over 1,500 years by young and old people, including > pregnant women without any report of harm to my knowledge. This alone make > me feel more comfortable using it. Sucralose is new however. Too new for me > to feel comfortable with it. <snip> Ah, the "to my knowledge" is the key part. Stick your head in the sand and you won't learn much. And do you really think we are stupid enough to believe anything at the Mercola site? SignatureType 2 http://users.bestweb.net/~jbove/ Well, I did ask you for some references. SignatureWinning against heart attack and stroke http://www.sonoscore.com Sonos, Stevia tastes nasty. And yes, there are some very negative reports about it. Being someone who has used herbal medicine in the past, when I first came to this newsgroup and asked about it, I got jumped on seriously. If you really want to know, do what Julie said and do a search on it. Meanwhile, you would do well not to take your chances with it, and most especially don't try and push it on this newsgroup. Splenda doesn't taste bad at all, and I am sure it has been tested more rigorously than Stevia ever was. As an example, are you aware that people used to drink Sassafras tea? Turned out that Sassafras is poisonous. So citing long use is not necessarily a valid argument. SignatureEvelyn (To reply to me personally, remove sox) > Well, I did ask you for some references. Thanks for the info. I'll look into it further... SignatureWinning against heart attack and stroke http://www.sonoscore.com Here are some very nice refernces... > Hsieh MH, Chan P, Sue YM, Liu JC, Liang TH, Huang TY, Tomlinson B, Chow > MS, Kao PF, Chen YJ. [quoted text clipped - 92 lines] > How Sweet Is Stevia > <URL:http://www.life.ca/nl/83/stevia.html> SignatureWinning against heart attack and stroke http://www.sonoscore.com Fri, 19 Mar 2004 23:10:33 GMT in article <J5L6c.594$DV6.10@twister.nyc.rr.com> "Evelyn Ruut" <mama-lionsox@hvc.rr.com> wrote: >Sonos, > >Stevia tastes nasty. And yes, there are some very negative reports about >it. Could you mention some? BTW, I don't think stevia tastes nasty, but de gustibus non est disputandum. -- Matti Narkia > Fri, 19 Mar 2004 23:10:33 GMT in article > <J5L6c.594$DV6.10@twister.nyc.rr.com> "Evelyn Ruut" [quoted text clipped - 8 lines] > > BTW, I don't think stevia tastes nasty, but de gustibus non est disputandum. It surely doesn't taste as good as Splenda. I threw out a whole bottle of Stevia when I got that. SignatureEvelyn (To reply to me personally, remove sox) > -- > Matti Narkia I mix unsweetened baking cocoa with stevia into soy milk and really like it. http://www.ghirardelli.com/products_bakecocoa2.html http://www.iherb.com/steviabalance.html SignatureWinning against heart attack and stroke http://www.sonoscore.com >I mix unsweetened baking cocoa with stevia into soy milk and really like it. I do the cocoa and soy milk combo without the stevia and love it. The taste of the stevia is masked by the others. > It surely doesn't taste as good as Splenda. I threw out a whole bottle of > Stevia when I got that. Agreed. Stevia tastes so nasty it makes me almost gag just thinking about it! And I bought the kind that everyone told me had the most agreeable taste too. :-) Debbie > Agreed. Stevia tastes so nasty it makes me almost gag just thinking about > it! And I bought the kind that everyone told me had the most agreeable taste > too. :-) Did you ever try it (NOW) after they enhanced the refinement? As I recall, when we both first tried it, it was a pale tan powder, with a disagreeable aftertaste. Later they refined it to a bright white powder, and I find it very acceptable to mix with other sweeteners. Signaturejamie (jamiemck@newsguy.com) "There's a seeker born every minute." > Did you ever try it (NOW) after they enhanced the refinement? As I > recall, when we both first tried it, it was a pale tan powder, with a > disagreeable aftertaste. Later they refined it to a bright white powder, > and I find it very acceptable to mix with other sweeteners. I did try the NOW white powder. I was able to tolerate it in pumpkin pie, where the various spices helped mask the taste, but for other things I still found the taste too strong. Debbie Matti Narkia burbled across the ether: > Fri, 19 Mar 2004 23:10:33 GMT in article > <J5L6c.594$DV6.10@twister.nyc.rr.com> "Evelyn Ruut" [quoted text clipped - 6 lines] >> > Could you mention some? From a re-curring post by jamie which I find pertinent: ------------------ There's a saying in toxicology, "the dose determines the poison." Almost everything is toxic in large enough amounts, and non-toxic in small enough amounts. If you could manage to eat 10 pounds of spinach in one sitting, the oxalic acid could kill you. The "potential harmful effects" from Splenda are a bunch of maybe it's this and maybe it's that conjecture, at quackery sites like Mercola. Mercola copied it from holistmed.com holistmed.com is Mark Gold's anti-sweetener site, mostly filled with well known net-lunatic Betty Martini's unsubstantiated claims against aspartame, with expanded unsubstantiated claims against other sweeteners (including the persuasive but fake World Health Organization conference "document" on aspartame authored by Betty, but often attributed to the fictional Nancy Markle, which has been going around the net for the past decade). Myself, I use both stevia and Splenda (and ace-K and saccharin), but stevia is not super-duper-safe just because it's extracted from a plant. Here's some less than wonderful info on stevia that you won't find on holisticquackmed.com: (you can easily find all these in a PubMed search): Stevia was shown in studies to shrink the testicles and lower the sperm count of male rats. Steviol has shown mutagenic properties in rodent assays in some studies. Stevia was shown in studies to increase renal plasma flow in rats and cause systemic renal vasodilation, consistent with impairment of autregulatory kidney function. Quoting from http://www.foodstandards.gov.uk/bulletin/no120/stevia.htm The European Commission considered an application for its use in 1998. The data was considered by the EC Scientific Committee for Food (SCF) who indicated that the extract has the potential to produce adverse effects in the male reproductive system that could affect fertility and that steviol, a metabolite of stevioside produced by human gut microflora, damages DNA. The Committee therefore concluded that stevioside was not acceptable as a sweetener. As stevioside and other Stevia products are not listed as permitted sweeteners in the relevant regulations, it is illegal to sell them as sweeteners in the UK. Stevioside was first considered by the SCF for approval for use as a sweetener within the EU in 1985 and again in 1989. On both occasions the Committee raised a number of questions and concluded that, based on the submitted documentation, it's use could not be accepted. Stevioside extracts from Stevia rebaudiana leaves were also considered as toxicologically not acceptable. (end quote) So, choose your "poisons," folks. ------------------- Signaturerevek www.geocities.com/tanirevek/LowCarb.html lowcarbing since June 2002 5'2" 41 F 165+/too much/size seven petite please "It must be considered that there is nothing more difficult to carry out, nor more doubtful of success, nor more dangerous to handle, than to initiate a new order of things. For the reformer has enemies in all those who profit by the old order, and only lukewarm defenders in all those who would profit by the new order. This lukewarmness arising partly from fear of their adversaries, who have the laws in their favor; and partly from the incredulity of mankind, who do not truly believe in anything new until they have had actual experience of it." -Niccolo Machiavelli, "The Prince", Chapter 6, 1537 > > Stevia has been used for over 1,500 years by young and old people, > including [quoted text clipped - 12 lines] > Type 2 > http://users.bestweb.net/~jbove/ Julie, if the Mercola site forecast sunshine in the desert, I'd bring my umbrella. http://www.foodstandards.gov.uk enter stevia into the search engine. Read and learn. Learn why stevia is banned in the European Union and other places. Learn what happens to reproductive organs in the male. Learn what happens to mitochondria when exposed to stevioside. We've done our research, sonos, now go do yours. Vicki > http://www.foodstandards.gov.uk > > enter stevia into the search engine. I did. Thanks. Like the FDA, your link is to a government agency who must also contend with lobby efforts of a multibillion dollar industy. SignatureWinning against heart attack and stroke http://www.sonoscore.com Fri, 19 Mar 2004 18:31:33 -0500 in article <405B82D5.36BE9748@netscape.net> >> > Stevia has been used for over 1,500 years by young and old people, >> including [quoted text clipped - 23 lines] >other places. Learn what happens to reproductive organs in the male. >Learn what happens to mitochondria when exposed to stevioside. As far as I understand some negative effects have been produced in rodents by giving them gigantic doses of steviol or stevioside. Even so, conflicting results have also been produced. Some studies suggest that stevia and stevioside have antiglycemic, antihypertensive, antiviral and even anticancer effects, although cancer has also been observed in rodents in connection with gigantic doses. In general, it seems that no negative effects have been proven with the doses applicable for human consumption. EU's stand seems to be that because some negative effects have been noticed with huge doses, stevia should not be permitted until its safety has been proven more convincingly. Here a couple of links found from the web site you provided: <URL:http://www.foodstandards.gov.uk/news/pressreleases/stevioside> A citation: "An application to market a component of the leaves known as Stevioside was also rejected by the Commission on safety grounds. Stevioside has been shown to decrease fertility in male rats. Additionally, Steviol, which is a metabolite of Stevioside, has been reported to cause cancer when fed at very high doses to rodents (up to 1000mg per kg of body weight - this is 1500 times greater than the average daily dose of these products consumed by a person weighing 60kg)." <URL:http://www.foodstandards.gov.uk/multimedia/webpage/stevia> A couple of excerpts: "The data considered by the Committee indicated that the extract has the potential to produce adverse effects in the male reproductive system that could affect fertility and that a metabolite produced by the human gut microflora, steviol, is genotoxic (ie. damages DNA). [...] The ACNFP agreed with the opinion of the Belgian Authorities and recommended that the product should not be approved due to lack of information supporting its safety, a view that was shared by a number of other Member States. The application was subsequently referred to the SCF. The SCF concluded in June 1999 that the information submitted on the plant products was insufficient with regard to specification and standardisation of the commercial product and contained no safety studies." On this page there is also a link to this letter: <URL:http://archive.food.gov.uk/maff/archive/food/novel/stevreb.htm> Below a rather comprehensive collection of stevia related Medline references: Toxicology references --------------------- Hagiwara A, Fukushima S, Kitaori M, Shibata M, Ito N. Effects of three sweeteners on rat urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)-nitrosamine. Gann. 1984 Sep;75(9):763-8. PMID: 6500232 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=6500232> Ito N, Fukushima S, Shirai T, Hagiwara A, Imaida K. Drugs, food additives and natural products as promoters in rat urinary bladder carcinogenesis. IARC Sci Publ. 1984;(56):399-407. PMID: 6536604 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=6536604> Xili L, Chengjiany B, Eryi X, Reiming S, Yuengming W, Haodong S, Zhiyian H. Chronic oral toxicity and carcinogenicity study of stevioside in rats. Food Chem Toxicol. 1992 Nov;30(11):957-65. PMID: 1473789 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=1473789> Aze Y, Toyoda K, Imaida K, Hayashi S, Imazawa T, Hayashi Y, Takahashi M. [Subchronic oral toxicity study of stevioside in F344 rats] Eisei Shikenjo Hokoku. 1991;(109):48-54. Japanese. PMID: 1364404 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=1364404> Matsui M, Matsui K, Kawasaki Y, Oda Y, Noguchi T, Kitagawa Y, Sawada M, Hayashi M, Nohmi T, Yoshihira K, Ishidate M Jr, Sofuni T. Evaluation of the genotoxicity of stevioside and steviol using six in vitro and one in vivo mutagenicity assays. Mutagenesis. 1996 Nov;11(6):573-9. PMID: 8962427 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8 962427&dopt=Abstract> Matsui M, Matsui K, Nohmi T, Mizusawa H, Ishidate M. [Mutagenicity of steviol: an analytical approach using the Southern blotting system] Eisei Shikenjo Hokoku. 1989;(107):83-7. Japanese. PMID: 2700079 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=2700079> Klongpanichpak S, Temcharoen P, Toskulkao C, Apibal S, Glinsukon T. Lack of mutagenicity of stevioside and steviol in Salmonella typhimurium TA 98 and TA 100. J Med Assoc Thai. 1997 Sep;80 Suppl 1:S121-8. PMID: 9347659 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9 347659&dopt=Abstract> Suttajit M, Vinitketkaumnuen U, Meevatee U, Buddhasukh D. Mutagenicity and human chromosomal effect of stevioside, a sweetener from Stevia rebaudiana Bertoni. Environ Health Perspect. 1993 Oct;101 Suppl 3:53-6. PMID: 8143647 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=8143647> Procinska E, Bridges BA, Hanson JR. Interpretation of results with the 8-azaguanine resistance system in Salmonella typhimurium: no evidence for direct acting mutagenesis by 15-oxosteviol, a possible metabolite of steviol. Mutagenesis. 1991 Mar;6(2):165-7. PMID: 2056919 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=2056919> Yodyingyuad V, Bunyawong S. Effect of stevioside on growth and reproduction. Hum Reprod. 1991 Jan;6(1):158-65. PMID: 1874950 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=1874950> Sekihashi K, Saitoh H, Sasaki Y. [Genotoxicity studies of stevia extract and steviol by the comet assay] J Toxicol Sci. 2002 Dec;27 Suppl 1:1-8. Japanese. PMID: 12533916 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 2533916&dopt=Abstract> Toyoda K, Matsui H, Shoda T, Uneyama C, Takada K, Takahashi M. Assessment of the carcinogenicity of stevioside in F344 rats. Food Chem Toxicol. 1997 Jun;35(6):597-603. PMID: 9225018 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=9225018> Toskulkao C, Chaturat L, Temcharoen P, Glinsukon T. Acute toxicity of stevioside, a natural sweetener, and its metabolite, steviol, in several animal species. Drug Chem Toxicol. 1997 Feb-May;20(1-2):31-44. PMID: 9183561 [PubMed - indexed for MEDLINE <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=9183561> Krejci ME, Koechel DA. Acute effects of carboxyatractyloside and stevioside, inhibitors of mitochondrial ADP/ATP translocation, on renal function and ultrastructure in pentobarbital-anesthetized dogs. Toxicology. 1992;72(3):299-313. PMID: 1585384 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=1585384> Wasuntarawat C, Temcharoen P, Toskulkao C, Mungkornkarn P, Suttajit M, Glinsukon T. Developmental toxicity of steviol, a metabolite of stevioside, in the hamster. Drug Chem Toxicol. 1998 May;21(2):207-22. PMID: 9598301 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=9598301> Usami M, Sakemi K, Kawashima K, Tsuda M, Ohno Y. [Teratogenicity study of stevioside in rats] Eisei Shikenjo Hokoku. 1995;(113):31-5. Japanese. PMID: 8717225 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=8717225> Sekihashi K, Saitoh H, Sasaki Y. [Genotoxicity studies of stevia extract and steviol by the comet assay] J Toxicol Sci. 2002 Dec;27 Suppl 1:1-8. Japanese. PMID: 12533916 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 2533916&dopt=Abstract> Yasukawa K, Kitanaka S, Seo S. Inhibitory effect of stevioside on tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Biol Pharm Bull. 2002 Nov;25(11):1488-90. PMID: 12419967 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 2419967&dopt=Abstract> Geuns JM, Bruggeman V, Buyse JG. Effect of stevioside and steviol on the developing broiler embryos. J Agric Food Chem. 2003 Aug 13;51(17):5162-7. PMID: 12903985 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=12903985> Braguini WL, Gomes MA, de Oliveira BH, Carnieri EG, Rocha ME, de Oliveira MB. Activity of isosteviol lactone on mitochondrial metabolism. Toxicol Lett. 2003 Jun 5;143(1):83-92. PMID: 12697384 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=12697384> Melis MS. Effects of chronic administration of Stevia rebaudiana on fertility in rats. J Ethnopharmacol. 1999 Nov 1;67(2):157-61. PMID: 10619379 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 0619379&dopt=Abstract> Oliveira-Filho RM, Uehara OA, Minetti CA, Valle LB. Chronic administration of aqueous extract of Stevia rebaudiana (Bert.) Bertoni in rats: endocrine effects. Gen Pharmacol. 1989;20(2):187-91. PMID: 2785472 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=2785472> Schvartzman JB, Krimer DB, Moreno Azorero R. Cytological effects of some medicinal plants used in the control of fertility. Experientia. 1977 May 15;33(5):663-5. PMID: 862810 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=862810> Aritajat S, Kaweewat K, Manosroi J, Manosroi A. Dominant lethal test in rats treated with some plant extracts. Southeast Asian J Trop Med Public Health. 2000;31 Suppl 1:171-3. PMID: 11414451 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=11414451> Chemistry reference ------------------- Geuns JM. Stevioside. Phytochemistry. 2003 Nov;64(5):913-21. PMID: 14561506 [PubMed - in process] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 4561506&dopt=Abstract> Antiglycemic & antihypertensive effects related references ---------------------------------------------------------- Jeppesen PB, Gregersen S, Rolfsen SE, Jepsen M, Colombo M, Agger A, Xiao J, Kruhoffer M, Orntoft T, Hermansen K. Antihyperglycemic and blood pressure-reducing effects of stevioside in the diabetic Goto-Kakizaki rat. Metabolism. 2003 Mar;52(3):372-8. PMID: 12647278 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 2647278&dopt=Abstract> Liu JC, Kao PK, Chan P, Hsu YH, Hou CC, Lien GS, Hsieh MH, Chen YJ, Cheng JT. Mechanism of the antihypertensive effect of stevioside in anesthetized dogs. Pharmacology. 2003 Jan;67(1):14-20. PMID: 12444299 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 2444299&dopt=Abstract> Hsu YH, Liu JC, Kao PF, Lee CN, Chen YJ, Hsieh MH, Chan P. Antihypertensive effect of stevioside in different strains of hypertensive rats. Zhonghua Yi Xue Za Zhi (Taipei). 2002 Jan;65(1):1-6. PMID: 11939668 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 1939668&dopt=Abstract> Jeppesen PB, Gregersen S, Alstrup KK, Hermansen K. Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: studies in the diabetic Goto-Kakizaki (GK) rats. Phytomedicine. 2002 Jan;9(1):9-14. PMID: 11924770 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 1924770&dopt=Abstract> Lee CN, Wong KL, Liu JC, Chen YJ, Cheng JT, Chan P. Inhibitory effect of stevioside on calcium influx to produce antihypertension. Planta Med. 2001 Dec;67(9):796-9. PMID: 11745013 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 1745013&dopt=Abstract> Jeppesen PB, Gregersen S, Poulsen CR, Hermansen K. Stevioside acts directly on pancreatic beta cells to secrete insulin: actions independent of cyclic adenosine monophosphate and adenosine triphosphate-sensitive K+-channel activity. Metabolism. 2000 Feb;49(2):208-14. PMID: 10690946 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 0690946&dopt=Abstract> Chan P, Xu DY, Liu JC, Chen YJ, Tomlinson B, Huang WP, Cheng JT. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci. 1998;63(19):1679-84. PMID: 9806223 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9 806223&dopt=Abstract> Toskulkao C, Sutheerawattananon M, Piyachaturawat P. Inhibitory effect of steviol, a metabolite of stevioside, on glucose absorption in everted hamster intestine in vitro. Toxicol Lett. 1995 Oct;80(1-3):153-9. PMID: 7482583 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=7482583> Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res. 1996 May;29(5):669-75. PMID: 9033821 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9 033821&dopt=Abstract> Lailerd N, Saengsirisuwan V, Sloniger JA, Toskulkao C, Henriksen EJ. Effects of stevioside on glucose transport activity in insulin-sensitive and insulin-resistant rat skeletal muscle. Metabolism. 2004 Jan;53(1):101-7. PMID: 14681850 [PubMed - in process] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 4681850&dopt=Abstract> Wong KL, Chan P, Yang HY, Hsu FL, Liu IM, Cheng YW, Cheng JT. Isosteviol acts on potassium channels to relax isolated aortic strips of Wistar rat. Life Sci. 2004 Mar 26;74(19):2379-87. PMID: 14998715 [PubMed - in process] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=14998715> Wong KL, Yang HY, Chan P, Cheng TH, Liu JC, Hsu FL, Liu IM, Cheng YW, Cheng JT. Isosteviol as a potassium channel opener to lower intracellular calcium concentrations in cultured aortic smooth muscle cells. Planta Med. 2004 Feb;70(2):108-12. PMID: 14994186 [PubMed - in process] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=14994186> Chan P, Tomlinson B, Chen YJ, Liu JC, Hsieh MH, Cheng JT. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol. 2000 Sep;50(3):215-20. PMID: 10971305 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 0971305&dopt=Abstract> Hsieh MH, Chan P, Sue YM, Liu JC, Liang TH, Huang TY, Tomlinson B, Chow MS, Kao PF, Chen YJ. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: A two-year, randomized, placebo-controlled study. Clin Ther. 2003 Nov;25(11):2797-808. PMID: 14693305 [PubMed - in process] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 4693305&dopt=Abstract> Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism. 2004 Jan;53(1):73-6. PMID: 14681845 [PubMed - in process] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 4681845&dopt=Abstract> Anti-viral activity related reference ------------------------------------- Takahashi K, Matsuda M, Ohashi K, Taniguchi K, Nakagomi O, Abe Y, Mori S, Sato N, Okutani K, Shigeta S. Analysis of anti-rotavirus activity of extract from Stevia rebaudiana. Antiviral Res. 2001 Jan;49(1):15-24. PMID: 11166857 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 1166857&dopt=Abstract> Links to stevia articles on the web ----------------------------------- Herbal tea lowers blood pressure, say doctors The China Post, Monday, April 2, 2001 <URL:http://www.taiwanheadlines.gov.tw/20010402/20010402s6.html> "A doctor at Taipei's Municipal Wan Fang Hospital (MWFH) yesterday said that herbal tea made from the sweet leaves of a plant called stevia is effective in lowering high blood pressure. Dr Chen Pao-lo, a cardiologist at MWFH, said after a series of clinical studies, he has found that stevia tea not only lowers the blood pressure of patients suffering from hypertension, it also lacks the side effects normally associated with blood-pressure lowering medicine. According to Chen, stevia was originally grown in Brazil and Paraguay before it was imported to mainland China's Xinjiang for mass cultivation decades ago. Chen pointed out that even when used over a long period, stevia tea does not threaten patients' blood sugar levels. Since stevia has been used as health food for more than 20 years with no noticeable side effects, Chen reckoned the plant could be made into blood-pressure lowering medicine safely as well." The Nutraceutical Corner.........Stevia: A Sweet Choice for Some <URL:http://sun.science.wayne.edu/~nfs/news/basfsp00.htm#Stevia> Stevia Sweetener, a Sugar Alternative <URL:http://nutrition.about.com/library/weekly/aa092099.htm> Stevia Research <URL:http://herbsforhealth.about.com/cs/herbsasfood/a/aa121997_2.htm> Stevia : by Ray Sahelian MD , stevia sweetener stevia recipes stevia cooking <URL:http://www.raysahelian.com/stevia.html> Stevia, Herb Monograph - Flora Health Herb Encyclopedia <URL:http://www.florahealth.com/flora/home/canada/healthinformation/encyclopedias/Ste via.asp> Monograph : Stevia rebaudiana (vaatii ilmaisen rekisteröitymisen) <URL:http://www.phytotherapies.org/monograph_detail.cfm?id=262> Medicinal herbFAQ Part 2/7 (etsi sivulta Stevia) <URL:http://www.faqs.org/faqs/medicinal-herbs/part2/> Stevia rebaudiana <URL:http://www.rain-tree.com/stevia.htm> Stevia - The Natural Sweetener <URL:http://www.healthy.net/nutrit/kitchen/foods/stevia.asp> Stevia - Frequently asked questions <URL:http://www.stepa.be/faqs.html> How Sweet Is Stevia <URL:http://www.life.ca/nl/83/stevia.html> -- Matti Narkia >Stevia has been used for over 1,500 years by young and old people, including >pregnant women without any report of harm to my knowledge. This alone make >me feel more comfortable using it. Sucralose is new however. Too new for me >to feel comfortable with it. for 1500 years. and yet it only recently made it to market. if you have to lie to support your shilling don't be surprised when people write you off as a fruit cake. Sonos said this... > Stevia has been used for over 1,500 years by young and old people, including > pregnant women without any report of harm to my knowledge. This alone make > me feel more comfortable using it. Sucralose is new however. Too new for me > to feel comfortable with it. Stevia is banned in the EU as it is dangerous, and selling it in Hong Kong carries a prison sentence for the same reasons. Stevia is toxic. R SignatureLife's Rich Pageant www.flyingrat.net Sat, 20 Mar 2004 01:53:31 -0000 in article <MPG.1ac5b479ee52e55989ca9@news.individual.net> Flying Rat <me9@privacy.net> wrote: >Sonos said this... >> [quoted text clipped - 7 lines] > >Stevia is toxic. This has not been proven with doses applicable for human consumption, see the references I've provided. Most of the stevia toxicology studies indicate lack of toxicity. On the other hand stevia seems to have antihypertensieve, anticlycemic, and possibly other beneficial health effects (antiviral, anticancer). -- Matti Narkia > Sat, 20 Mar 2004 01:53:31 -0000 in article ><MPG.1ac5b479ee52e55989ca9@news.individual.net> Flying Rat <me9@privacy.net> [quoted text clipped - 3 lines] > This has not been proven with doses applicable for human consumption, see > the references I've provided. So this statement is valid if it's about stevia, but the same statment is invalid if applied to artificial sweeteners? There's a saying in toxicology, "the dose determines the poison." Almost everything is toxic in large enough amounts, and non-toxic in small enough amounts. Signaturejamie (jamiemck@newsguy.com) "There's a seeker born every minute." > Stevia is banned in the EU as it is dangerous, and selling it in Hong > Kong carries a prison sentence for the same reasons. > > Stevia is toxic. I think you are mixing politics with science. The two are not compatible. SignatureWinning against heart attack and stroke http://www.sonoscore.com >> Stevia is banned in the EU as it is dangerous, and selling it in Hong >> Kong carries a prison sentence for the same reasons. >> >> Stevia is toxic. > >I think you are mixing politics with science. The two are not compatible. but if aspartame were banned and not stevia, then you would not be making that statement. > Stevia has been used for over 1,500 years by young and old people, including > pregnant women without any report of harm to my knowledge. This alone make > me feel more comfortable using it. Sucralose is new however. Too new for me > to feel comfortable with it. Splenda has been in widespread use in Canada for about 15 years, and you might note that there aren't vast amounts of Canadian diabetics dying of diseases or growing an extra head since its release. Mercola is a major alarmist quack and a fruitcake. Signaturejamie (jamiemck@newsguy.com) "There's a seeker born every minute." > why not try stevia instead? Splenda is a sugar molecule with a chlorine > pasted on it. A tasty invention, but is it safe? Oh, Splenda is safe. And yet we know Stevia is not. Funny that you would be pushing it then. SignatureType 2 http://users.bestweb.net/~jbove/ > And yet we know Stevia is not How do we know that stevia is not safe? SignatureWinning against heart attack and stroke http://www.sonoscore.com > > And yet we know Stevia is not > > How do we know that stevia is not safe? *sigh* Do a search. I don't feel like providing the links yet again. For one thing, it can't be sold legally as a sweetener in the USA and is banned in many other countries. That in itself should tell you something. If you really want to know, then look it up. But you probably don't want to know since I suspect you are just another Stevia troll. SignatureType 2 http://users.bestweb.net/~jbove/ Fri, 19 Mar 2004 17:29:43 -0500 in article <105mtecdqbkcmff@corp.supernews.com> "Julie Bove" <jnospambove@bestweb.net> wrote: >> > And yet we know Stevia is not >> [quoted text clipped - 5 lines] >really want to know, then look it up. But you probably don't want to know >since I suspect you are just another Stevia troll. Actually, we do not know that stevia is not safe. Its "unsafety" has not been conclusively proven, see the Medline references I provided in my other message. But EU is not convinced that stevia is safe either, therefore it wants more convincing evidence about its safety before permitting it. Some Asian nations, for example Japan, where a large number of stevia studies have been conducted, do not have such reservations and regard stevia as a safe sweetener. The other side of the coin is that according many studies stevia seems to have considerable beneficial health effects, for example antihyperglycemic and antihypertensive effects. The antifertility issues, if proven real, also have two sides: they may be beneficial for older couples who do not want more children, but younger couples may have to exercise some caution in the use of stevia, especially if they already have fertility problems. -- Matti Narkia Matti Narkia burbled across the ether: > Actually, we do not know that stevia is not safe. Its "unsafety" has > not been conclusively proven, Ya know, you can say the exact same thing about sucralose. Exact. Why is it that setvia has to be proven to be unsafe, yet all other sweeteners have to be proven safe? Double standard if you ask me. Signaturerevek www.geocities.com/tanirevek/LowCarb.html lowcarbing since June 2002 5'2" 41 F 165+/too much/size seven petite please After all is said and done, more is said than done. Sat, 20 Mar 2004 03:43:59 -0600 in article <c3h3p0$273htj$1@ID-190183.news.uni-berlin.de> "revek" <pphillps1962@hotmail.com> wrote: >Matti Narkia burbled across the ether: >> Actually, we do not know that stevia is not safe. Its "unsafety" has [quoted text clipped - 3 lines] >is it that setvia has to be proven to be unsafe, yet all other >sweeteners have to be proven safe? Double standard if you ask me. Not at all. EU's stand is that stevia has to be proven safe more conclusively before it can be permitted. Therefore no double standard. -- Matti Narkia Matti Narkia burbled across the ether: > Sat, 20 Mar 2004 03:43:59 -0600 in article > <c3h3p0$273htj$1@ID-190183.news.uni-berlin.de> "revek" [quoted text clipped - 10 lines] > Not at all. EU's stand is that stevia has to be proven safe more > conclusively before it can be permitted. Therefore no double standard. I'm not talking about the EU's stand. I'm talking about your statement about it's unsafety being unproven. Signaturerevek www.geocities.com/tanirevek/LowCarb.html lowcarbing since June 2002 5'2" 41 F 165+/too much/size seven petite please A rant a day keeps the white coats away. -KellyAnn Sat, 20 Mar 2004 04:29:22 -0600 in article <c3h6e3$288nt6$1@ID-190183.news.uni-berlin.de> "revek" <pphillps1962@hotmail.com> wrote: >Matti Narkia burbled across the ether: >> Sat, 20 Mar 2004 03:43:59 -0600 in article [quoted text clipped - 14 lines] >I'm not talking about the EU's stand. I'm talking about your statement >about it's unsafety being unproven. It is unproven. That had to be emphasized, because unproven or false claims like 1) "Stevia is toxic" 2) "Stevia is banned in the EU as it is dangerous" were presented in this thread. -- Matti Narkia > Sat, 20 Mar 2004 04:29:22 -0600 in article > <c3h6e3$288nt6$1@ID-190183.news.uni-berlin.de> "revek" [quoted text clipped - 11 lines] > > were presented in this thread. I just think that it tastes nasty. --Bryan > > Sat, 20 Mar 2004 04:29:22 -0600 in article > > <c3h6e3$288nt6$1@ID-190183.news.uni-berlin.de> "revek" [quoted text clipped - 15 lines] > > --Bryan Me too, Bryan. There are those who believe that ONLY herbal "natural" products should be ingested. That includes a wide variety of untested, unproven, and often very dangerous and even poisonous products, (though it is granted that there ARE some perfectly safe and effective herbs out there). By the same token, there are those who believe that ONLY legal, pharmaceutically tested products are any good, (though some of them are pretty dangerous and poisonous as well) I just quit taking Lipitor, a well tested and highly recommended drug because it gave me horrible hot flushes and made me so weak I could hardly walk at times. I choose to believe that we are taking our chances no matter what we take, and that it is always a case of "buyer beware" and as always YMMV. SignatureEvelyn (To reply to me personally, remove sox) >why not try stevia instead? Splenda is a sugar molecule with a chlorine >pasted on it. A tasty invention, but is it safe? now the stevia shills are attacking splenda and have nothing to back up their "suspicions" so give it a few minutes to a couple of days and they will post the same fiction about splenda they made up about aspartame. stevia is banned in teh USA from being sold a s sweetener and is banned completely in several locations outside the USA. personally I thought stevia was bitter tasting thing that should never be lied about and called a sweetener. > why not try stevia instead? Splenda is a sugar molecule with a chlorine > pasted on it. A tasty invention, but is it safe? Combining atoms into molecules changes their physical properties. Sodium and Chloride are both toxic to humans, yet we sprinkle salt on our food all the time. E > > why not try stevia instead? Splenda is a sugar molecule with a chlorine > > pasted on it. A tasty invention, but is it safe? [quoted text clipped - 4 lines] > > E Here we go again with the "chlorine is deadly" crowd showing up. I have been swimming in chlorinated pools all my life and I'm not dead yet. And please stop the cross posting. Pat in TX > why not try stevia instead? Splenda is a sugar molecule with a chlorine > pasted on it. A tasty invention, but is it safe? Stevia is not so perfectly safe as various pages would have you believe, either. Choose your poisons, folks. Stevia was rejected by the European Commission Scientific Committee for Food (EU equivalent to our FDA) in 1998 for its potential to produce adverse affects on the male reproductive system, and that steviol (produced when stevia is digested) damages DNA. [quote from a UK government bulletin copied below post] Stevia was shown in studies to shrink the testicles and lower the sperm count of male rats. Steviol has shown mutagenic properties in rodent assays in some studies. Stevia was shown in studies to increase renal plasma flow in rats and cause systemic renal vasodilation, consistent with impairment of autoregulatory kidney function. That said, I use both Splenda and stevia. Personally, I think it's very slightly safer to use a variety of sweeteners, than any one sweetener. The human body has a remarkable capacity to handle minute amounts of unhealthy and even toxic substances. The "dose" of sweetener in a packet is only a few thousandths of a gram. There's a saying in toxicology: "the dose makes the poison." There's enough oxalic acid in 20 pounds of spinach to *kill* an adult, but nobody could eat that much spinach. ------- Quoted from http://www.foodstandards.gov.uk/bulletin/no120/stevia.htm The European Commission considered an application for its use in 1998. The data was considered by the EC Scientific Committee for Food (SCF) who indicated that the extract has the potential to produce adverse effects in the male reproductive system that could affect fertility and that steviol, a metabolite of stevioside produced by human gut microflora, damages DNA. The Committee therefore concluded that stevioside was not acceptable as a sweetener. As stevioside and other Stevia products are not listed as permitted sweeteners in the relevant regulations, it is illegal to sell them as sweeteners in the UK. Stevioside was first considered by the SCF for approval for use as a sweetener within the EU in 1985 and again in 1989. On both occasions the Committee raised a number of questions and concluded that, based on the submitted documentation, it's use could not be accepted. Stevioside extracts from Stevia rebaudiana leaves were also considered as toxicologically not acceptable. (end quote) Signaturejamie (jamiemck@newsguy.com) "There's a seeker born every minute." In alt.support.diet.low-carb jamie <jamie@sure.spam-me-silly.net> wrote: >Personally, I think it's very slightly safer to use a variety of >sweeteners, than any one sweetener. It's also easier to use no sweetener. 20 Mar 2004 22:09:23 GMT in article <slrnc5pg8i.np.jamie@bozo2.local.net> >> why not try stevia instead? Splenda is a sugar molecule with a chlorine >> pasted on it. A tasty invention, but is it safe? [quoted text clipped - 17 lines] >and cause systemic renal vasodilation, consistent with impairment of >autoregulatory kidney function. Here is the abstract of a very recent toxicology review of Stevia: Geuns JM. Stevioside. Phytochemistry. 2003 Nov;64(5):913-21. PMID: 14561506 [PubMed - in process] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 4561506&dopt=Abstract> Laboratory of Plant Physiology, Catholic University of Leuven, Kasteelpark Arenberg 31, B 3001 Leuven, Belgium. jan.geuns@bio.kuleuven.ac.be Abstract: "Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana (Bertoni) Bertoni. The literature about Stevia, the occurrence of its sweeteners, their biosynthetic pathway and toxicological aspects are discussed. Injection experiments or perfusion experiments of organs are considered as not relevant for the use of Stevia or stevioside as food, and therefore these studies are not included in this review. The metabolism of stevioside is discussed in relation with the possible formation of steviol. Different mutagenicity studies as well as studies on carcinogenicity are discussed. Acute and subacute toxicity studies revealed a very low toxicity of Stevia and stevioside. Fertility and teratogenicity studies are discussed as well as the effects on the bio-availability of other nutrients in the diet. The conclusion is that Stevia and stevioside are safe when used as a sweetener. It is suited for both diabetics, and PKU patients, as well as for obese persons intending to lose weight by avoiding sugar supplements in the diet. No allergic reactions to it seem to exist." -- Matti Narkia > 20 Mar 2004 22:09:23 GMT in article <slrnc5pg8i.np.jamie@bozo2.local.net> > [quoted text clipped - 26 lines] > Phytochemistry. 2003 Nov;64(5):913-21. > PMID: 14561506 [PubMed - in process] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&li st_uids=14561506&dopt=Abstract> > Laboratory of Plant Physiology, Catholic University of Leuven, Kasteelpark > Arenberg 31, B 3001 Leuven, Belgium. jan.geuns@bio.kuleuven.ac.be [quoted text clipped - 22 lines] > -- > Matti Narkia It still tastes horrible, with a bitter aftertaste. I will still take my chances with the legitimately tested stuff. Aspartame or Splenda, they both taste better. SignatureEvelyn (To reply to me personally, remove sox) Sun, 21 Mar 2004 03:33:30 GMT in article <e287c.1003$t_4.1339441@twister.nyc.rr.com> "Evelyn Ruut" <mama-lionsox@hvc.rr.com> wrote: >> 20 Mar 2004 22:09:23 GMT in article <slrnc5pg8i.np.jamie@bozo2.local.net> >> [quoted text clipped - 60 lines] >chances with the legitimately tested stuff. Aspartame or Splenda, they >both taste better. Really? I kind of like Stevia's taste and prefer if to other sweeteners. Perhaps you should try another brand of Stevia, because there are taste differences depending on the manufacturing process. The page Stevia Rebaudiana - the taste (stevia page 3) <URL:http://www.formerfatguy.com/articles/stevia-taste.asp> claims that the whole leaf extract tastes best. But there are taste differences even among the whole leaf products. An excerpt form the page Life With Stevia: How Sweet It Is! <URL:http://www.healthfree.com/stevia7.htm> : "While there is no question that stevia is sweet, many users will admit that they have also experienced a bitter aftertaste from some brands. In fact, one of the problems with stevia products currently available from health food retailers is that many of them just plain do not taste good. They often have a distinct grassy taste, with varying degrees of bitterness associated with the sweet. These differences in quality may partly be a result of using non-Paraguayan stevia, partly due to poor extraction and processing techniques and partly the result of ignorance on the part of manufactureres concerning the real nature of the stevia plant. One knowledgeable producer of stevia products is attempting to set up industry standards for grading stevia leaves according to their quality. Grade A stevia would be the highest quality, an extremely sweet grade, with little bitter aftertaste and a concentrated degree of sweetness. This grade is very difficult to obtain due to climatic conditions that prevent harvesting at just the right time. Grade B would be a little less sweet with some minor deterioration of the leaf. Most of the best stevia arriving in the United States from Paraguay is Grade B. The vast majority of stevia sold in the United States would be classified as Grade C, a poor grade with a good deal of grassy, bitter flavor. Extracts of Grade C are particularly unpalatable, possessing far too much bitterness. Manufacturers often try to dress them up with other flavoring agents, but such attempts seldom work. Once you have tasted a premium stevia, you will never be satisfied by lesser products. The bitter principles are actually found in the veins of the leaf, while the leafy material between the veins contains the sweet components. Great care must be taken during production of stevia extract to avoid contaminating the sweet with the bitter. This pertains as much to extraction as it does to milling." -- Matti Narkia >>It still tastes horrible, with a bitter aftertaste. I will still take my >>chances with the legitimately tested stuff. Aspartame or Splenda, they [quoted text clipped - 3 lines] >Perhaps you should try another brand of Stevia, because there are taste >differences depending on the manufacturing process. The page nah it's just simpler to buy what is readily available. no need to waste money on something that was already proven disagreeable to the user, would incur further costs and risks of dissatisfaction and incur the cost of shipping. we can buy splenda, sweet-n-low, and nutrasweet at any grocery. we can also request they carry it if it is not currently stocked. Can't do either with stevia. I also don't like the taste and wouldn't bother asking a grocer to carry it. > Sun, 21 Mar 2004 03:33:30 GMT in article > <e287c.1003$t_4.1339441@twister.nyc.rr.com> "Evelyn Ruut" [quoted text clipped - 68 lines] > Perhaps you should try another brand of Stevia, because there are taste > differences depending on the manufacturing process. The page I am happy with Splenda completely. I drink soda made with it, and it tastes great. I bought the liquid Splenda in the tiny dropper bottle and the flavor is almost indistinguishable from sugar. One drop in my tea is all I need. I have some Splenda packets I carry in my handbag for when I am out, and in a pinch I can even deal with Equal (which most restaurants have) if I have to. Why risk the health dangers when there is a well tested product readily available? I see no point. SignatureEvelyn (To reply to me personally, remove sox) Sun, 21 Mar 2004 13:55:52 GMT in article <I9h7c.1867$1C1.1400573@twister.nyc.rr.com> "Evelyn Ruut" <mama-lionsox@hvc.rr.com> wrote: >> Sun, 21 Mar 2004 03:33:30 GMT in article >> <e287c.1003$t_4.1339441@twister.nyc.rr.com> "Evelyn Ruut" [quoted text clipped - 5 lines] > >I am happy with Splenda completely. Good for you. Others, including me, may prefer potentially safer alternative such as Stevia, which may have additional health benefits such as antihypertensive and anti-glycemic effects. >I drink soda made with it, and it tastes great. I bought the liquid Splenda >in the tiny dropper bottle and the flavor is almost indistinguishable from >sugar. One drop in my tea is all I need. I don't drink any soda or any other carbonated drinks, they may have some negative health effects such as reduced bone mineral density and increased risk of osteoporosis. For tea or coffee I didn't use any sweetener for more than 15 years until I became interested in Stevia because of potential health benefits associated with it. Unfortunately Stevia is not sold here in Finland (in EU), so I have to order it from abroad. >I have some Splenda packets I carry in my handbag for when I am out, and in >a pinch I can even deal with Equal (which most restaurants have) if I have >to. > >Why risk the health dangers when there is a well tested product readily >available? I see no point. That's funny because I don't want to risk my health with artificial sweeteners when it is possible (although not easy here in EU) to obtain a natural sweetener which has safely been used for over 1500 years, has been thoroughly researched in Japan for example, where it is extensively used as a sweetener, and which is assessed as completely safe in the most recent toxicological review from last November: Geuns JM. Stevioside. Phytochemistry. 2003 Nov;64(5):913-21. PMID: 14561506 [PubMed - in process] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 4561506&dopt=Abstract> -- Matti Narkia Sun, 21 Mar 2004 17:29:22 +0200 in article <71cr50l3iq6rtkhunpatiib7ovfc1c648k@4ax.com> Matti Narkia <mnng@despammed.com> wrote: >Sun, 21 Mar 2004 13:55:52 GMT in article ><I9h7c.1867$1C1.1400573@twister.nyc.rr.com> "Evelyn Ruut" [quoted text clipped - 9 lines] >than 15 years until I became interested in Stevia because of potential >health benefits associated with it. As a demonstration about the potential health benefits of Stevia I enclose the following abstracts of human clinical trials in the treatment of type 2 diabetes and mild hypertension with stevioside: Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism. 2004 Jan;53(1):73-6. PMID: 14681845 [PubMed - in process] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 4681845&dopt=Abstract> "Stevioside is present in the plant Stevia rebaudiana Bertoni (SrB). Extracts of SrB have been used for the treatment of diabetes in, for example, Brazil, although a positive effect on glucose metabolism has not been unequivocally demonstrated. We studied the acute effects of stevioside in type 2 diabetic patients. We hypothesize that supplementation with stevioside to a test meal causes a reduction in postprandial blood glucose. Twelve type 2 diabetic patients were included in an acute, paired cross-over study. A standard test meal was supplemented with either 1 g of stevioside or 1 g of maize starch (control). Blood samples were drawn at 30 minutes before and for 240 minutes after ingestion of the test meal. Compared to control, stevioside reduced the incremental area under the glucose response curve by 18% (P =.013). The insulinogenic index (AUC(i,insulin)/AUC(i,glucose)) was increased by approximately 40% by stevioside compared to control (P <.001). Stevioside tended to decrease glucagon levels, while it did not significantly alter the area under the insulin, glucagon-like peptide 1, and glucose-dependent insulinotropic polypeptide curves. In conclusion, stevioside reduces postprandial blood glucose levels in type 2 diabetic patients, indicating beneficial effects on the glucose metabolism. Stevioside may be advantageous in the treatment of type 2 diabetes." Hsieh MH, Chan P, Sue YM, Liu JC, Liang TH, Huang TY, Tomlinson B, Chow MS, Kao PF, Chen YJ. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: A two-year, randomized, placebo-controlled study. Clin Ther. 2003 Nov;25(11):2797-808. PMID: 14693305 [PubMed - in process] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 4693305&dopt=Abstract> "BACKGROUND: Stevioside, a natural glycoside isolated from the plant Stevia rebaudiana Bertoni, has been used as a commercial sweetening agent in Japan and Brazil for >20 years. Previous animal and human studies have indicated that stevioside has an antihypertensive effect. OBJECTIVES: This study was undertaken to investigate the long-term (2-year) efficacy and tolerability of stevioside in patients with mild essential hypertension. Secondary objectives were to determine the effects of stevioside on left ventricular mass index (LVMI) and quality of life (QOL). METHODS: This was a multicenter, randomized, double-blind, placebo-controlled trial in Chinese men and women aged between 20 and 75 years with mild essential hypertension (systolic blood pressure [SBP] 140-159 mm Hg and diastolic blood pressure [DBP] 90-99 mm Hg). Patients took capsules containing 500 mg stevioside powder or placebo 3 times daily for 2 years. Blood pressure was measured at monthly clinic visits; patients were also encouraged to monitor blood pressure at home using an automated device. LVMI was determined by 2-dimensional echocardiography at baseline and after 1 and 2 years of treatment. QOL was assessed using the Medical Outcomes Study 36- Item Short-Form Health Survey. Electrocardiographic, laboratory, and QOL parameters were assessed at the beginning of treatment, and at 6 months, 1 year, and 2 years. RESULTS: One hundred seventy-four patients (87 men, 87 women) were enrolled in the study, and 168 completed it: 82 (42 men, 40 women; mean [SD] age, 52 [7] years) in the stevioside group and 86 (44 women, 42 men; mean age, 53 [7] years) in the placebo group. After 2 years, the stevioside group had significant decreases in mean (SD) SBP and DBP compared with baseline (SBP, from 150 [7.3] to 140 [6.8] mm Hg; DBP, from 95 [4.2] to 89 [3.2] mm Hg; P < 0.05) and compared with placebo (P < 0.05). Based on patients' records of self-monitored blood pressure, these effects were noted beginning approximately 1 week after the start of treatment and persisted throughout the study. There were no significant changes in body mass index or blood biochemistry, and the results of laboratory tests were similar in the 2 groups throughout the study. No significant difference in the incidence of adverse effects was noted between groups, and QOL scores were significantly improved overall with stevioside compared with placebo (P < 0.001). Neither group had a significant change in mean LVMI. However, after 2 years, 6 of 52 patients (11.5%) in the stevioside group had left ventricular hypertrophy (LVH), compared with 17 of 50 patients (34.0%) in the placebo group (P < 0.001). Of those who did not have LVH at baseline, 3 of 46 patients (6.5%) in the stevioside group had developed LVH after 2 years, compared with 9 of 37 patients (24.3%) in the placebo group (P < 0.001). CONCLUSIONS: In this 2-year study in Chinese patients with mild hypertension, oral stevioside significantly decreased SBP and DBP compared with placebo. QOL was improved, and no significant adverse effects were noted." Chan P, Tomlinson B, Chen YJ, Liu JC, Hsieh MH, Cheng JT. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol. 2000 Sep;50(3):215-20. PMID: 10971305 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 0971305&dopt=Abstract> "AIMS: Stevioside is a natural plant glycoside isolated from the plant Stevia rebaudiana which has been commercialized as a sweetener in Japan for more than 20 years. Previous animal studies have shown that stevioside has an antihypertensive effect. This study was to designed to evaluate the effect of stevioside in human hypertension. METHODS: A multicentre, randomized, double-blind, placebo-controlled study was undertaken. This study group consisted of 106 Chinese hypertensive subjects with diastolic blood pressure between 95 and 110 mmHg and ages ranging from 28 to 75 years with 60 subjects (men 34, women 26; mean +/- s.d., 54.1+/-3.8 years) allocated to active treatment and 46 (men 19, women 27; mean +/- s.d., 53.7+/-4.1 years) to placebo treatment. Each subject was given capsules containing stevioside (250 mg) or placebo thrice daily and followed-up at monthly intervals for 1 year. RESULTS: After 3 months, the systolic and diastolic blood pressure of the stevioside group decreased significantly (systolic: 166.0+/-9.4-152.6+/-6.8 mmHg; diastolic: 104.7 +/- 5.2-90.3+/-3.6 mmHg, P<0.05), and the effect persisted during the whole year. Blood biochemistry parameters including lipid and glucose showed no significant changes. No significant adverse effect was observed and quality of life assessment showed no deterioration. CONCLUSIONS: This study shows that oral stevioside is a well tolerated and effective modality that may be considered as an alternative or supplementary therapy for patients with hypertension." -- Matti Narkia I just got the point. Matti Narkia is a spammer who is trying to PUSH Stevia. PLONK! Bye Matti Narkia SignatureEvelyn (To reply to me personally, remove sox) > Sun, 21 Mar 2004 03:33:30 GMT in article > <e287c.1003$t_4.1339441@twister.nyc.rr.com> "Evelyn Ruut" [quoted text clipped - 115 lines] > -- > Matti Narkia Sun, 21 Mar 2004 14:02:59 GMT in article <ngh7c.1873$1C1.1402169@twister.nyc.rr.com> "Evelyn Ruut" <mama-lionsox@hvc.rr.com> wrote: >I just got the point. Matti Narkia is a spammer who is trying to PUSH >Stevia. It seems that Evelyn Ruut is unable to carry on conversations where views opposing to her are presented. I happen to live in Finland, which is in EU and where selling of Stevia is not permitted. So much for your ridiculous accusation. Fortunately I've been able to get Stevia for my own use from USA now and then to be able to assess its suitability for my own use and enjoy its potential health benefits which for me mean more that its use as sweetener. Before I started using Stevia I did not use any sweeteners for more than 15 years. Now when my supply of Stevia has run out, I have no problem coping without sweetenera until my next order of Stevia will arrive from USA. -- Matti Narkia > I just got the point. Matti Narkia is a spammer who is trying to PUSH > Stevia. > > PLONK! > > Bye Matti Narkia Evelyn, you're wrong about Matti. What you got was science and differing viewpoints from yours. Matti always presents solid information documented by research or an opinion, but there's no doubt about which is which. No spamming going on here. Matti is a very good contributor. Pastorio > > I just got the point. Matti Narkia is a spammer who is trying to PUSH > > Stevia. [quoted text clipped - 11 lines] > > Pastorio On your recommendation I will un-block Matti. Thanks for the heads up. There are so many spammers who target this newsgroup it probably made me punchy. :-) SignatureEvelyn (To reply to me personally, remove sox) Sun, 21 Mar 2004 02:54:16 +0200 in article <ampp501eduq4b9m0c1savjddle8rko5c5a@4ax.com> Matti Narkia <mnng@despammed.com> wrote: >Here is the abstract of a very recent toxicology review of Stevia: > [quoted text clipped - 27 lines] > intending to lose weight by avoiding sugar supplements in the > diet. No allergic reactions to it seem to exist." Already in 1998 Dr. Andrew Weil wrote on the page Sweet on Stevia? <URL:http://www.drweil.com/app/cda/drw_cda.html?command=TodayQA&pt=Question&questionI d=3258> about Stevia as follows: "Today's Question Q: Sweet on Stevia? Are you familiar with stevia? I'd like to know how to use the herb as a sweetener. I'd especially like to know if it can be used as a sweetener in baked goods, such as cookies. -- Elena W. Today's Answer A:(Published 08/31/1998) (Published 5/22/97) Stevia comes from a shrub native to Paraguay, Stevia rebaudiana. It also grows in Brazil and Argentina, and is now widely cultivated in China. The leaves have been used for centuries by native peoples to make sweet teas, or to sweeten other foods, with no evidence of adverse reactions. In Japan, Brazil and other countries, people use the extracted sweet principle, called stevioside, as a table sweetener. It tastes faintly of licorice and is many, many times sweeter than sucrose. Stevia has minimal calories and is reputed to have beneficial effects on fat absorption and blood pressure. The Food and Drug Administration has been trying to suppress stevia for years, some say at the instigation of the manufacturer of aspartame. The agency still refuses to classify it as a safe food additive, a position I find untenable. The easiest way to use stevia is to dissolve the granular white powder in water and use drops as a sweetening solution. You can use it in anything -- on your cereal, in baked goods, whatever. But you do need to adjust recipes to make it work, because you're using just a few drops of liquid instead of a cup or so of sugar. One reference I've seen replaces 1 cup of sugar with 1 1/2 to 2 tablespoons of the herb, or 1/4 teaspoon of the white powder extract. I'd check with your supplier to get information on the best way to do this without ending up with flat muffins or rock-hard cookies. Stevia is especially useful for people who cannot tolerate sugar, including diabetics. And despite the FDA's import ban on foods sweetened with stevia, you can find it sold as a dietary supplement." -- Matti Narkia Sun, 21 Mar 2004 14:41:24 +0200 in article <i13r50h7jr31bfgc6rsuel2q5ji72ejker@4ax.com> Matti Narkia <mnng@despammed.com> wrote: >Already in 1998 Dr. Andrew Weil wrote on the page > [quoted text clipped - 48 lines] > foods sweetened with stevia, you can find it sold as a dietary > supplement." Another article by Dr. Weil, which comments both Splenda and Stevia: Taste-Testing the New Artificial Sweetener? <URL:http://www.drweil.com/app/cda/drw_cda.html-command=TodayQA-questionId=3426> "Today's Question Q: Taste-Testing the New Artificial Sweetener? What is this new sweetener " sucralose" ? Is it just as bad as aspartame? Better? -- Anonymous Today's Answer A: (Published 12/08/1998) Sucralose is the latest in no-cal sugar substitutes that supposedly taste like the real thing without an aftertaste. The FDA approved it earlier this year, making it the first artificial sweetener to pass muster in 10 years. Based on what I have read, sucralose does seem to be safer than aspartame and other artificial sweeteners. The product of British research in which scientists substituted chlorine atoms for three of sugar's eight hydrogen-oxygen pairs, sucralose is a substance 600 times sweeter than sugar that maintains its sweetness under a wide range of temperatures, making it a useful option for cooking and baking. Nevertheless, I still say that the best noncaloric sweetener is stevia. Stevia is an herb in the chrysanthemum family native to Paraguay that you can buy as leaves or as a granular white powder. To use it, you dissolve the powder in water and use drops as a sweetening solution. Stevia has virtually no calories, is safe for use by diabetics and is widely used as a sweetener around the world, especially Japan. A few drops of the liquid provides the sweetness of an entire cup of sugar. Unfortunately, the Food and Drug Administration has been actively suppressing stevia for years, perhaps at the instigation of manufacturers of the artificial sweeteners. For whatever reason, despite years of evidence to the contrary, the agency still refuses to classify it as a safe food additive, permitting stevia to be sold only a dietary supplement. Even so, you can substitute stevia for sugar in most recipes by replacing one cup of sugar with 1 1/2 to 2 tablespoons of dissolved stevia or 1/4 teaspoon of the white powder extract. I suggest that you check with your supplier before cooking or baking with stevia to determine exact equivalencies." Another Dr. Weil's article about Splenda: A Safer Sweetener? <URL:http://www.drweil.com/app/cda/drw_cda.html-command=TodayQA-questionId=64359> -- Matti Narkia Sun, 21 Mar 2004 02:54:16 +0200 in article <ampp501eduq4b9m0c1savjddle8rko5c5a@4ax.com> Matti Narkia <mnng@despammed.com> wrote: >Here is the abstract of a very recent toxicology review of Stevia: > [quoted text clipped - 27 lines] > intending to lose weight by avoiding sugar supplements in the > diet. No allergic reactions to it seem to exist." I happen to have the full text of the above review article in PDF form, which I could lend to interested individuals, please contact me by email. Below the references from the full text article: References Alves et al., 1979. L.M. Alves and M. Ruddat, The presence of gibberelling A20 in Stevia rebaudiana and its significance for the biological activity of steviol. Plant Cell Physiol. 20 (1979), pp. 123130. Akashi and Yokoyama, 1975. H. Akashi and Y. Yokoyama, Security of dried-leaf extracts of Stevia. Toxicological tests. Food Industry 18 (1975), pp. 3443. Anonymous, 1996. Anonymous, 1996. Voedingsaanbevelingen voor België, (D/1996/7795/12) Ed. G. De Backer, Zevecotestraat 43, B-9830 Sint-Martens-Latem, pp 77. Aze et al., 1991. Y. Aze, K. Toyoda, K. Imaida, S. Hayashi, T. Imazawa, Y. Hayashi and M. Takahashi, Subchronic oral toxicity study of stevioside in F344 rats. Bull. Nat. Inst. Hyg. Sc 109 (1991), pp. 4854. Bearder et al., 1975. J.R. Bearder, J. MacMillan and C.M. Wels, The metabolism of steviol to 13-hydroxylated ent-gibberellanes and ent-keuranes. Phytochemistry 14 (1975), pp. 17411748. Abstract | Abstract + References | PDF (810 K) Boeckh-Haebisch, 1992. E.M.A. Boeckh-Haebisch, Pharmacological Trial of a concentrated crude extract of Stevia rebaudiana (Bert) Bertoni in healthy volunteers. Arq. Biol. Tecnol. 35 2 (1992), pp. 299314. Bracht et al., 1985. A.M. Bracht, F.S. Kemmelmeier, E.L. Ishii, M. Alvarez and A. Bracht, Effect of Stevia rebaudiana natural products on cellular and sub-cellular metabolism. Arq. Biol. Tecnol. 28 (1985), pp. 431455. Brandle et al., 2002. J.E. Brandle, A. Richman, A.K. Swanson and B.P. Chapman, Leaf ESTs from Stevia rebaudiana: a resource for gene discovery in diterpene synthesis. Plant Mol. Biol. 50 (2002), pp. 613622. Chan et al., 2000. P. Chan, B. Tomlinson, Y.-J. Chen, J.-C. Liu, M.-H. Hsieh and J.-T. Cheng, A double-blind placebo-controlled study pf the effectiveness and tolerability of oral stevioside in human hypertension. Br. J. Clin. Pharmacol. 50 (2000), pp. 215220. Chan et al., 1998. P. Chan, D.-Y. Xu, J.-C. Liu, Y.-J. Chen, B. Tomlinson, W.-P. Huang and J.-T. Cheng, The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci. 63 (1998), pp. 16791684. Abstract | Full Text + Links | PDF (440 K) Compadre et al., 1988. C.M. Compadre, R.A. Hussain, N.P.D. Nanayakkara, J.M. Pezzuto and A.D. Kinghorn, Mass spectral analysis of some derivatives and in vitro metabolites of steviol, the aglycone of the natural sweeteners, stevioside, rebaudioside A and rubusoside. Biomed. Environ. Mass Spectrom. 15 (1988), pp. 211222. Curi et al., 1986. R. Curi, M. Alvarez, R.B. Bazotte, L.M. Botion, J.L. Godoy and A. Bracht, Effect of Stevia rebaudiana on glucose tolerance in normal adult humans. Brazilian J. Med. Biol. Res. 19 (1986), pp. 771774. Das et al., 1992. S. Das, A.K. Das, R.A. Murphy, I.C. Punwani, M.P. Nasution and A.D. Kinghorn, Evaluation of the Cariogenic Potential of the Intense Natural Sweeteners Stevioside and Rebaudioside A. Caries Res. 26 (1992), pp. 363366. de Oliveira and Strapasson, 1996. B.H. de Oliveira and R.A. Strapasson, Biotransformation of isosteviol by Fusarium verticilloides. Phytochemistry 43 (1996), pp. 393395. Abstract | Abstract + References | PDF (191 K) de Oliveira et al., 1999. B.H. de Oliveira, M.C. dos Santos and P.C. 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Buyse, Metabolism of stevioside by chickens. J. Agric. Food Chem. 51 (2003), pp. 10951101. Geuns et al., in press b. Geuns, J.M.C., Bruggeman, V., and Buyse, J.G. Effect of stevioside and steviol on the developing broiler embryos. J. Agric. Food Chem. (in press b). Gianfagna et al., 1983. T. Gianfagna, J.A.D. Zeevaart and W.J. Lusk, Synthesis of [2H]gibberellins from steviol using the fungus Gibberella fujikuroi. Phytochemistry 22 (1983), pp. 427430. Abstract | Full Text + Links | PDF (452 K) Hagiwara et al., 1984. A. Hagiwara, S. Fukushima and M. Kitaori, Effects of the three sweeteners on rats urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)-nitrosamine. Gann. 75 (1984), pp. 763768. Hersenhorn et al., 1997. J. Hersenhorn, M. Zohar, B. Crammer, Z. Ziv, V. Weinstein, Y. Kleifeld, Y. Lavan and R. Ikan, Plant-growth regulators derived from the sweetener stevioside. Plant Growth Regulation 23 (1997), pp. 173178. Hutapea et al., 1997. A.M. Hutapea, C. Toskulkao, D. 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Seo, Inhibitory effect of stevioside on tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Biol. Pharm. Bull. 25 (2002), pp. 14881490. Yodyingyuad et al., 1991. V. Yodyingyuad and S. Bunyawong, Effect of stevioside on growth and reproduction. Human Reproduction 6 (1991), pp. 158165. -- Matti Narkia > As you may know, Splenda is available in a tablet form in many > countries. > If enough people contacted Johnson & Johnson, maybe they would start > selling them here. I have not asked for tablets, but I have written to J&J multiple times asking for a liquid version of Splenda (to avoid all the added maltodextrin filler in the splenda powder) but every time I have gotten back a canned response that "there is no market for it". I suspect I'd get the same response about the tablets. Debbie I just sent them an email asking "when" the tablets would be available due to the inconvenience of either toting your own packets or a restaurant not having splenda. Maybe if we all do that it will spark something? denise > > As you may know, Splenda is available in a tablet form in many > > countries. [quoted text clipped - 8 lines] > > Debbie > > As you may know, Splenda is available in a tablet form in many > > countries. [quoted text clipped - 8 lines] > > Debbie BS, there's no market! They are just control freaks! > BS, there's no market! They are just control freaks! If they would sell the tablets and or liquid to me at the wholesale price (the price they sell them to distributors in other countries), I would be glad to set up a mail order business to tap into that "no market". |
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