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yogurt and weight loss

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Doug Skrecky - 24 Mar 2005 05:09 GMT
[Looks like yogurt may be helpful on a low or moderate protein diet, but
yields no benefit on a high protein diet.]

Int J Obes Relat Metab Disord. 2005 Apr;29(4):391-7.
Dairy augmentation of total and central fat loss in obese subjects.
BACKGROUND AND OBJECTIVE:: We have previously demonstrated an antiobesity
effect of dietary Ca; this is largely mediated by Ca suppression of
calcitriol levels, resulting in reduced adipocyte intracellular Ca(2+)
and, consequently, a coordinated increase in lipid utilization and
decrease in lipogenesis. Notably, dairy Ca is markedly more effective
than other Ca sources. DESIGN:: Obese subjects were placed on balanced
deficit (-500 kcal/day) diets and randomized to control (400-500 mg
Ca/day; n=16) or yogurt (1100 mg Ca/day; n=18) treatments for 12 weeks.
Dietary macronutrients and fiber were held constant at the US average.
MEASUREMENTS:: Body weight, body fat and fat distribution (by dual-energy
X-ray absorptiometry), blood pressure and circulating lipids were
measured at baseline and after 12 weeks of intervention. RESULTS:: Fat
loss was markedly increased on the yogurt diet (-4.43+/-0.47 vs
-2.75+/-0.73 kg in yogurt and control groups; P<0.005) while lean tissue
loss was reduced by 31% on the yogurt diet. Trunk fat loss was augmented
by 81% on the yogurt vs control diet (P<0.001), and this was reflected in
a markedly greater reduction in waist circumference (-3.99+/-0.48 vs
-0.58+/-1.04 cm, P<0.001). Further, the fraction of fat lost from the
trunk was higher on the yogurt diet vs control (P<0.005). CONCLUSION::
Isocaloric substitution of yogurt for other foods significantly augments
fat loss and reduces central adiposity during energy
restriction.International Journal of Obesity (2005) 29, 391-397.
doi:10.1038/sj.ijo.0802880 Published online 11 January 2005.

Int J Obes Relat Metab Disord. 2005 Feb 15; [Epub ahead of print]
Effect of calcium and dairy foods in high protein, energy-restricted
diets on weight loss and metabolic parameters in overweight adults.
OBJECTIVE:: To compare the effects two high-protein (HP) diets that
differ in dietary calcium and protein source on weight loss, body
composition, glucose and lipid metabolism, markers of liver function,
fibrinolysis and endothelial function and blood pressure. DESIGN::
Randomized, parallel study (12 wk of energy restriction, 4 wk of energy
balance) of high dairy protein/high-calcium (DP, 2400 mg Ca/d) and high
mixed protein/moderate calcium (MP, 500 mg Ca/d) diets (5.5 MJ/d, 34%
protein, 41% carbohydrate, 24% fat). SUBJECTS:: In all, 50 healthy,
overweight (age 25-64 y; body mass index 25-35 kg/m(2);) males (n=20) and
females (n=30). RESULTS:: Loss of total weight (-9.7+/-3.8 kg), fat mass
(-8.3+/-0.4 kg) and lean mass (-1.6+/-0.3 kg) were independent of dietary
group. Improvements in fasting insulin, lipids, systolic/diastolic blood
pressure, and markers of liver function, fibrinolysis and endothelial
function were independent of dietary intervention. CONCLUSIONS::
Increased dietary calcium/dairy foods in an energy-restricted, HP diet
does not affect weight loss or body composition. Weight reduction
following increased protein diets is associated with beneficial metabolic
outcomes that are not affected by protein source.International Journal of
Obesity advance online publication, 15 February 2005;
doi:10.1038/sj.ijo.0802895.
Carol Frilegh - 24 Mar 2005 06:40 GMT
> [Looks like yogurt may be helpful on a low or moderate protein diet, but
> yields no benefit on a high protein diet.]

When yogurt is home made and incubated 24 hours almost all the lactose
is consumed.

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Polar Light - 24 Mar 2005 10:49 GMT
> [Looks like yogurt may be helpful on a low or moderate protein diet, but
> yields no benefit on a high protein diet.]

I eat yogurt because I like it, it's very versatile & low-cal, if it speeds
up weight loss so much the better. What's never been clear to me is the role
of protein in weight loss, having read so much about it everywhere. I know
you need a certain amount every day to avoid burning lean muscle mass but as
to what this amount may be... some say 50g/day, others .5g/lb, or is it
5g/lb of IDEAL weight? or is it GOAL weight? I mean *standard* requirements,
not for bodybuilding.

I've always heard you lose more weight on high protein diets, some say it's
because protein requires more calories for breakdown, others say this isn't
so... The paragraph below seems to suggest higher protein diets are better
for weight loss after all. I wonder if this is *really* the case.

> Increased dietary calcium/dairy foods in an energy-restricted, HP diet
> does not affect weight loss or body composition. Weight reduction
> following increased protein diets is associated with beneficial metabolic
> outcomes that are not affected by protein source.International Journal of
> Obesity advance online publication, 15 February 2005;
> doi:10.1038/sj.ijo.0802895.
Olafur Pall Olafsson - 26 Mar 2005 08:09 GMT
> I've always heard you lose more weight on high protein diets, some say it's
> because protein requires more calories for breakdown, others say this isn't
> so... The paragraph below seems to suggest higher protein diets are better
> for weight loss after all. I wonder if this is *really* the case.

You generally lose more weight on high protein diets.  Although protein
contains about 4 calories/g about one third of that energy actually
gets used to convert the other two thirds to accessible energy for the
body.

The protein you eat is broken down to amino acids in the digestive
track.  In order to use these amino acids as energy your body has to
either directly oxidize them, or first convert them to glucose by
gluconeogenesis in the liver to make them available as energy for the
rest of the body.  Converting amino acids to glucose costs energy and
the energy gained from directly oxidizing amino acids in the liver is
used to fuel this convertion of amino acids to glucose.  The net effect
is that only about two thirds of the energy remains available as a fuel
source for the body.  See the abstract below for details.

Physiol Rev. 1992 Apr;72(2):419-48.

Quantitative analysis of amino acid oxidation and related
gluconeogenesis in
humans.

Jungas RL, Halperin ML, Brosnan JT.

Department of Physiology, University of Connecticut Health Center,
Farmington.

Significant gaps remain in our knowledge of the pathways of amino acid
catabolism in humans. Further quantitative data describing amino acid
metabolism
in the kidney are especially needed as are further details concerning
the
pathways utilized for certain amino acids in liver. Sufficient data do
exist to
allow a broad picture of the overall process of amino acid oxidation to
be
developed along with approximate quantitative assessments of the role
played by
liver, muscle, kidney, and small intestine. Our analysis indicates that
amino
acids are the major fuel of liver, i.e., their oxidative conversion to
glucose
accounts for about one-half of the daily oxygen consumption of the
liver, and no
other fuel contributes nearly so importantly. The daily supply of amino
acids
provided in the diet cannot be totally oxidized to CO2 in the liver
because such
a process would provide far more ATP than the liver could utilize.
Instead, most
amino acids are oxidatively converted to glucose. This results in an
overall ATP
production during amino acid oxidation very nearly equal to the ATP
required to
convert amino acid carbon to glucose. Thus gluconeogenesis occurs
without either
a need for ATP from other fuels or an excessive ATP production that
could limit
the maximal rate of the process. The net effect of the oxidation of
amino acids
to glucose in the liver is to make nearly two-thirds of the total
energy
available from the oxidation of amino acids accessible to peripheral
tissues,
without necessitating that peripheral tissues synthesize the complex
array of
enzymes needed to support direct amino acid oxidation. As a balanced
mixture of
amino acids is oxidized in the liver, nearly all carbon from glucogenic
amino
acids flows into the mitochondrial aspartate pool and is actively
transported
out of the mitochondria via the aspartate-glutamate antiport linked to
proton
entry. In the cytoplasm the aspartate is converted to fumarate
utilizing urea
cycle enzymes; the fumarate flows via oxaloacetate to PEP and on to
glucose.
Thus carbon flow through the urea cycle is normally interlinked with
gluconeogenic carbon flow because these metabolic pathways share a
common step.
Liver mitochondria experience a severe nonvolatile acid load during
amino acid
oxidation. It is suggested that this acid load is alleviated mainly by
the
respiratory chain proton pump in a form of uncoupled
respiration.(ABSTRACT
TRUNCATED AT 400 WORDS)

Publication Types:
   Review
   Review, Tutorial

PMID: 1557428 [PubMed - indexed for MEDLINE]
Kofi - 26 Mar 2005 09:50 GMT
They omit the most interesting possibility that probiotics in the
yoghurt affected fat metabolism and absorption.  Gut flora have been
known to affect metabolism.  See
<http://www.pnas.org/cgi/content/full/101/44/15718>
joni - 26 Mar 2005 22:25 GMT
> They omit the most interesting possibility that probiotics in the
> yoghurt affected fat metabolism and absorption.  Gut flora have been
> known to affect metabolism.

Its not necessarily the protein in the yogurt (its really higher in
carbs with minimal protein), and its not the flora either, altho both
can be good reasons to eat yogurt.  New studies show that foods that
contain CALCIUM are important in losing bodyfat. Something in the
digestive enzymes of calcium rich foods helps the body to breakdown
stored bodyfat. Just when the dairy farmers were about to go bankrupt:
http://my.webmd.com/content/article/23/1728_56703

<<joni>>

---------------------------------

*If we could give every individual the right amount of nourishment and
exercise, not too little and not too much, we would have found the
safest way to health.*- Hippocrates c. 460 - 377 B.C.
Polar Light - 26 Mar 2005 23:24 GMT
>> They omit the most interesting possibility that probiotics in the
>> yoghurt affected fat metabolism and absorption.  Gut flora have been
[quoted text clipped - 7 lines]
> stored bodyfat. Just when the dairy farmers were about to go bankrupt:
> http://my.webmd.com/content/article/23/1728_56703

I've read the article, the study's not so new as it dates back to 2000. The
mice in the study had skimmed milk not yogurt, presumably any low-fat dairy
products (cottage cheese, quark, etc) would work equally well if it's the
calcium rather than the culture in yogurt. Still strange that calcium
supplements didn't work as well as dairy, I wonder if there's something else
in milk that increases absorption.
 
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